兰州地区空气质量及家庭环境因素与过敏性鼻炎的相关性研究
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兰州市第二人民医院

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兰州市科技计划项目(2022-ZD-15)


Study on the Correlation Between Air Quality, Household Environmental Factors, and Allergic Rhinitis in the Lanzhou Region
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1.The Second People'2.'3.s Hospital of Lanzhou City,Lanzhou,Gansu

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    摘要:

    目的:探讨兰州地区变应性鼻炎(AR)患病率特征,并分析其与空气质量指数(AQI)、家庭环境及生活习惯的相关性。方法:以2022年3月~2023年3月甘肃省第二人民医院确诊的528例AR患者为研究对象,收集兰州市环保局发布的同期AQI月均值(涵盖PM2.5、PM10、SO?等污染物),结合标准化问卷调查评估家庭环境与生活习惯。采用Logistic回归分析环境暴露因素的比值比,并通过Pearson相关性检验分析AR月就诊率与AQI的关联。结果:空气污染与AR显著相关,PM10(P<0.01)和PM2.5(p<0.01)均与AR 就诊率呈正相关,冬季燃煤污染期间AR就诊率最高(p<0.01)。室内潮湿、霉菌和吸烟显著增加AR风险(p<0.001),其中霉菌暴露(OR=3.02)和吸烟(OR=1.89)是主要影响因素。生活习惯对AR影响明显,冬季通风不足(p=0.02)增加AR风险,而夏季通风(p=0.04)和空气净化(p=0.001)有保护作用。结论:兰州地区AR高发与空气污染(PM2.5、PM10)及家庭环境暴露(潮湿、霉菌、吸烟)密切相关。建议加强区域性空气质量治理,推广室内防潮除霉措施,并倡导无烟家庭环境以降低AR发病率。

    Abstract:

    Objective:To investigate the prevalence characteristics of allergic rhinitis (AR) in the Lanzhou region and analyze its correlation with the air quality index (AQI), household environment, and lifestyle habits. Methods:A total of 528 AR patients diagnosed at the Second People"s Hospital of Gansu Province from March 2022 to March 2023 were included in this study. Monthly average AQI values during the study period, including PM2.5, PM10, SO?, and other pollutants, were obtained from the Lanzhou Environmental Protection Bureau. A standardized questionnaire was used to assess household environmental factors and lifestyle habits. Logistic regression analysis was conducted to calculate the odds ratios (ORs) of environmental exposure factors, while Pearson correlation analysis was performed to examine the association between the monthly AR consultation rate and AQI. Results:Air pollution was significantly associated with AR incidence, with PM?? (p<0.01) and PM2.5(p<0.01) positively correlated with AR consultation rates. The highest AR consultation rate was observed during winter coal combustion pollution periods (p<0.01). Indoor dampness, mold, and smoking significantly increased the risk of AR (p<0.001), with mold exposure (OR=3.02) and smoking (OR=1.89) identified as major risk factors. Lifestyle habits also played a critical role in AR occurrence, with insufficient ventilation in winter increasing AR risk (p=0.02), whereas summer ventilation (p=0.04) and air purification (p=0.001) exhibited protective effects.Conclusion:The high prevalence of AR in Lanzhou is closely related to air pollution (PM2.5, PM10) and household environmental exposures (dampness, mold, smoking). Strengthening regional air quality management, promoting indoor moisture and mold control measures, and advocating for smoke-free home environments are recommended to reduce AR incidence.

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  • 收稿日期:2025-07-30
  • 最后修改日期:2025-09-21
  • 录用日期:2025-09-22
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